nbS1 — anatomy

parameters ▾

stimulate

gain 0.50

background drive

tonic drive 35 pA noise σ 1.6 mV/√ms · background bombardment

network balance

exc. release · Ca²⁺ proxy 0.25 · recurrent smearing inhibitory gain 1.0× · error-unit precision GABA decay τ 8.0 ms

dendrite

dendritic leak g_L 2.0 nS basal coupling g_c 6.0 nS · sensory pathway apical coupling g_c 2.0 nS · prior precision NMDA : AMPA 2.5 NMDA decay τ 50 ms [Mg²⁺]_o 1.0 mM

apical Ca²⁺ spike

plateau current 0 pA · 0 = off ignition threshold -35 mV BAC window 20 ms · scoring only

plateau duration (40 ms) and dead time (60 ms) are fixed: the engine reads them live but the server's live-parameter set does not expose them.

intrinsic

per cell class, not per column: each slider moves every neuron relative to its own e-type value. the number is the cADpyr reference.

subthreshold adapt. a 2.0 nS spike adaptation b 60 pA adaptation τ_w 150 ms threshold V_T -50 mV

neuromodulation

5-HT_2A agonism 0.00 · dose

acts by scaling apical coupling g_c (×1→4) and noise σ (×1→2.6) from wherever they sit at dose 0. those receptors are densest on L5 apical tufts, and depolarising the tuft is what agonism does there. return to 0 to restore. this is prior precision.

ACh · attention 0.00 · level

acts by raising sensory drive (×1→2.5, nicotinic facilitation of thalamocortical terminals) and lowering inhibitory gain (×1→0.55, the VIP→SST disinhibitory motif). this is sensory precision, and it pulls against the dose above. the neuromodulation lens measures which one wins.

plasticity · STDP

potentiation A₊ 0.000 · pre before post depression A₋ 0.000 · post before pre window τ 20 ms ceiling w_max 3.0×

synapses changedoff

mean multiplier—

short-term depression

release prob. U 0.32 recovery τ_D 515 ms

display ▸

arbor detail — · thickest branches first cells drawn — attenuation λ (at 1 µm ⌀) 150 µm · paints between the 3 compartments floor -72 mV · raise to hide resting noise ceiling -42 mV brightness 2.4 playback speed 1.00× real time

compartment colour

soma basal apical axon · needs --axons

cortical theories ▸

evaluation metrics · —

nbS1 · anatomy ▸